Stan Wawrinka was knocked out in the first round at Rotterdam on Tuesday after losing in straight sets 6-4, 7-5 to Russia’s Karen Khachanov.

The three-time Grand Slam winner, playing in his first match since going down in a five-set epic to Marton Fucsovics at the Australian Open, was beaten by world number 21 Khachanov in fairly comfortable fashion.

Big-hitter Khachanov eased through the match without dropping a service game to eighth seed Wawrinka. The 24-year-old will face British qualifier Cameron Norrie in the last 16.

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Khachanov’s countryman and fourth seed Andrey Rublev strolled into the next round thanks to a 7-6 (8/1), 6-3 win over American qualifier Marcos Giron.

The in-form Russian will face former world number one Andy Murray in the second round.

“Andy is a true legend and I have a really good connection with him,” said Rublev. “I really like him as a person and as a player. He destroyed me once in the past (6-3, 6-0, 6-2 in 2017 Australian Open second round). I’m sure we’ll have great, long rallies and it will be a fight.”

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Second seed Stefanos Tsitsipas eased into round two with a 7-6 (7/4), 7-5 victory over Belarusian Egor Gerasimov.

The Greek, who beat Rafael Nadal en route to the Australian Open semi-finals last month, dropped his serve once in each set but did enough to set up a last-16 tie with Poland’s Hubert Hurkacz, who saw off Frenchman Adrian Mannarino 6-3, 7-6 (8/6).

“We’ve played a lot in the past. He’s a great opponent, he’s been giving me a hard time. It’s a challenge going into that match,” Tsitsipas said.

Results

First round

Borna Coric (CRO) bt Botic van de Zandschulp (NED) 6-4, 7-6 (7/4)

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Alex De Minaur (AUS) bt John Millman (AUS) 6-1, 6-4

Jeremy Chardy (FRA) bt Ugo Humbert (FRA) 4-6, 7-6 (7/5), 7-6 (7/4)

Andrey Rublev (RUS x4) bt Marcos Giron (USA) 7-6 (7/1), 6-3

Karen Khachanov (RUS) bt Stan Wawrinka (SUI x8) 6-4, 7-5

Hubert Hurkacz (POL) bt Adrian Mannarino (FRA) 6-3, 7-6 (8/6)

Stefanos Tsitsipas (GRE x2) bt Egor Gerasimov (BLR) 7-6 (7/4), 7-5